The Role of N-acetylcysteine Amide in Acute Graft-versus-host Disease Mouse Model
Rui He, Wenyi Zheng, Kicky Rozing, Carlos Fernández Moro, Xiaoli Li, Yikai Yin, Weiying Zhou, Samir EL Andaloussi, Svante Norgren, Ying Heng Zhao, Moustapha Hassan
This study investigates N-acetylcysteine amide (NACA) as a prophylactic treatment for acute GvHD in a mouse model, showing reduced disease severity and improved survival without affecting donor engraftment.
bioRxiv · Apr 7, 2025 · PreprintPharmacology & Toxicology