Author

S. A. Luther

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:CITE-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Spill· 1 shared B. Ludewig· 1 shared B. Seijo· 1 shared C. Jimenez-Luna· 1 shared C. Ronet· 1 shared C.-P. Heisenberg· 1 shared D. Zehn· 1 shared E. Hannezo· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. Spill

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Author profile →

4 papers

Recent·Most cited

Malt1-dependent cleavage of Tensin-3 controls B-cell adhesion and lymphomagenesis

M. Juilland, N. Alouche, I. Ubezzi, M. Gonzalez, T. Erdmann, G. Lenz, S. A. Luther, M. Thome

This study identifies Tensin-3 as a Malt1 substrate in B cells, showing that its cleavage regulates adhesion, antibody production, and lymphoma metastasis without affecting transcription.

bioRxiv · Sep 29, 2022 · PreprintImmunology

Orthogonal Gene Engineering Enables CD8+ T Cells to Control Tumors through a Novel PD-1+ TOX-indifferent Synthetic Effector State

J. Corria-Osorio, S. J. Carmona, E. Stefanidis, M. J. Andreatta, T. Muller, Y. Ortiz, B. Seijo, W. Castro, C. Jimenez-Luna, L. Scarpellino, C. Ronet, A. Spill, E. Lanitis, S. A. Luther, P. Romero, , G. Coukos

This study shows that orthogonal gene engineering of CD8+ T cells with IL-2 variant, PD1-decoy, and IL-33 enables tumor control through a novel PD-1+ TOX-indifferent synthetic effector state.

bioRxiv · Feb 18, 2022 · PreprintImmunology

Multi-tier mechanics control stromal adaptations in swelling lymph nodes

F. P. Assen, M. Hons, R. Hauschild, S. Shamipour, J. Abe, W. A. Kaufmann, T. Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, J. V. Stein, C.-P. Heisenberg, E. Hannezo, S. A. Luther, M. Sixt

The paper investigates how lymph nodes accommodate size increases during immune challenges by analyzing biomechanical adaptations of fibroblastic reticular cells and fibroblasts.

bioRxiv · Jul 28, 2021 · PreprintImmunology

Attenuation of chronic antiviral T cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

K. Schaeuble, H. Cannelle, S. Favre, H.-Y. Huang, S. Oberle, D. Zehn, S. A. Luther

The paper identifies lymph node fibroblastic reticular cells (FRC) as a source of COX2-dependent PGE2 that suppresses T cell responses during chronic infection.

bioRxiv · Oct 30, 2018Immunology