Author

H.-Y. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

A. I. Huerta· 1 shared A. Menna· 1 shared C. Chen· 1 shared C. Guo· 1 shared C. Kesten· 1 shared C. Li· 1 shared C. Ma· 1 shared C. Pikaard· 1 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPlant Biology

A. I. Huerta

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2 in vitro

H.-F. Chen, W.-J. Wang, C.-Y. Chen, W.-C. Chang, P.-R. Hsueh, S.-L. Peng, C.-S. Wu, Y. Chen, H.-Y. Huang, W.-J. Shen, S.-C. Wang, M.-C. Hung

This study identifies OPCs and punicalagin as potent inhibitors of SARS-CoV-2 infection, with punicalagin showing the strongest activity against omicron variants and viral entry.

bioRxiv · Jan 12, 2023Microbiology

Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA

Y.-C. Lou, H.-Y. Huang, H.-H. Yeh, W.-H. Chiang, C. Chen, K.-P. Wu

The paper reports a cryo-EM structure of a PmrA-dependent transcription activation complex and shows how PmrA interacts with DNA and RNA polymerase to activate gene transcription.

bioRxiv · Jul 20, 2022 · PreprintBiophysics

Impact of glycosylation on a broad-spectrum vaccine against SARS-CoV-2

H.-Y. Huang, H.-Y. Liao, X. Chen, S.-W. Wang, C.-W. Cheng, M. Shahed-Al-Mahmud, T.-H. Chen, J. M. Lo, Y.-M. Liu, Y.-M. Wu, H.-H. Ma, Y.-H. Chang, H.-Y. Tsai, Y.-C. Chou, Y.-P. Hsueh, , C.-H. Wong

This study shows that trimming N-glycans from the SARS-CoV-2 spike protein enhances immune responses and protection against variants in hACE2 mice.

bioRxiv · May 25, 2021 · PreprintMicrobiology

PTP-3(LAR PTPR) promotes intramolecular folding of SYD-2(liprin-α) to inactivate UNC-104(KIF1A) in neurons

M. Muthaiyan Shanmugam, S. N. Barmaver, H.-Y. Huang, O. Wagner

This study shows that PTP-3 promotes intramolecular folding of SYD-2, reducing its interaction with UNC-104 and slowing axonal transport in C. elegans neurons.

bioRxiv · Aug 2, 2019 · PreprintCell Biology

Reaction mechanisms of Pol IV, RDR2 and DCL3 drive RNA channeling in the siRNA-directed DNA methylation pathway

J. Singh, V. Mishra, F. Wang, H.-Y. Huang, C. Pikaard

bioRxiv · Jun 22, 2019Biochemistry

Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors

Y. Wang, J. Zhang, S. Ren, D. Sun, H.-Y. Huang, H. Wang, Y. Jin, F. Li, C. Zheng, L. Yang, L. Deng, Z. Jiang, T. Jiang, X. Han, S. Hou, , H. Ji

This study identifies BCAT1-mediated metabolic reprogramming as a mechanism of EGFR TKI resistance in lung cancer and shows that combining TKI with ROS-inducing agents can overcome resistance.

bioRxiv · May 15, 2019Cancer Biology

Pathogen-induced pH changes regulate the growth-defense balance of plants

C. Kesten, F. M. Gamez-Arjona, S. Scholl, A. Menna, S. Dora, A. I. Huerta, H.-Y. Huang, N. Tintor, T. Kinoshita, M. Rep, M. Krebs, K. Schumacher, C. Sanchez-Rodriguez

This study shows that pathogen-induced pH changes regulate plant growth and defense by modulating cellulose synthesis and fungal pathogenicity through COMPANION OF CELLULOSE SYNTHASE proteins.

bioRxiv · Feb 18, 2019Plant Biology

Attenuation of chronic antiviral T cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

K. Schaeuble, H. Cannelle, S. Favre, H.-Y. Huang, S. Oberle, D. Zehn, S. A. Luther

The paper identifies lymph node fibroblastic reticular cells (FRC) as a source of COX2-dependent PGE2 that suppresses T cell responses during chronic infection.

bioRxiv · Oct 30, 2018Immunology