Author

S. A. Mosure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Organism:human· 1

Frequent Co-Authors

J. Bass· 2 shared P. Munoz-Tello· 2 shared R. Brust· 2 shared A. A. Deniz· 1 shared B. MacTavish· 1 shared C. C. Williams· 1 shared D. J. Kojetin· 1 shared D. Kojetin· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiophysics

J. Bass

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2 papers

Recent·Most cited

Structural basis of interdomain communication in PPARγ

S. A. Mosure, P. Munoz-Tello, K.-T. Kuo, B. MacTavish, X. Yu, D. Scholl, C. C. Williams, T. S. Strutzenberg, J. Li, J. Bass, R. Brust, E. Kalkhoven, A. A. Deniz, P. R. Griffin, D. Kojetin

This study identifies a conserved Trp-Pro motif in PPARγ AF-1 that undergoes cis/trans isomerization, enabling interdomain communication with the LBD and affecting transcriptional activity.

bioRxiv · Jul 13, 2022 · PreprintBiophysics

Cooperative Cobinding of Synthetic and Natural Ligands to the Nuclear Receptor PPARγ

J. Shang, R. Brust, S. A. Mosure, J. Bass, P. Munoz-Tello, H. Lin, T. S. Hughes, M. Tang, Q. Ge, T. M. Kamekencka, D. J. Kojetin

The paper shows synthetic and natural ligands can bind cooperatively to PPARγ, altering its structure and function through a 'ligand link' to the omega loop.

bioRxiv · Nov 1, 2018Biochemistry