Author

S. A. Shukla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. J. Wu· 3 shared J. Forman· 2 shared P. Bachireddy· 2 shared A. Apffel· 1 shared A. Bosma-Moody· 1 shared A. Flaifel· 1 shared A. Gnirke· 1 shared A. H. Nassar· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

C. J. Wu

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Author profile →

3 papers

Recent·Most cited

Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors

Z. Bakouny, D. A. Braun, S. A. Shukla, W. Pan, X. Gao, Y. Hou, A. Flaifel, S. Tang, A. Bosma-Moody, M. X. He, N. Vokes, J. Nyman, W. Xie, A. H. Nassar, S. Abou Alaiwi, , T. H. Ho

This study characterizes the molecular features and immune profile of sarcomatoid and rhabdoid renal cell carcinoma, showing their responsiveness to immune checkpoint inhibitors and identifying key genetic and transcriptional determinants.

bioRxiv · May 28, 2020Cancer Biology

Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to graft-versus-leukemia

P. Bachireddy, C. Ennis, V. Nguyen, K. Clement, S. H. Gohil, S. A. Shukla, J. Forman, N. Barkas, S. Freeman, N. Bavli, L. Elagina, I. Leshchiner, A. W. Mohammad, L. Z. Rassenti, T. J. Kipps, , C. J. Wu

The paper investigates the evolutionary trajectories of chronic lymphocytic leukemia cells during resistance to graft-versus-leukemia, finding distinct genetic and epigenetic dynamics post-transplant compared to chemotherapy.

bioRxiv · Apr 9, 2020Cancer Biology

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

T. Ouspenskaia, T. Law, K. R. Clauser, S. Klaeger, S. Sarkizova, F. Aguet, B. Li, E. Christian, B. A. Knisbacher, P. M. Le, C. R. Hartigan, H. Keshishian, A. Apffel, G. Oliveira, W. Zhang, , A. Regev

The paper identifies thousands of novel unannotated proteins in cancer that contribute to the MHC I immunopeptidome, expanding potential targets for immunotherapy.

bioRxiv · Feb 12, 2020 · PreprintCancer Biology