Author

S. Castelino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Organism:yeast· 1

Frequent Co-Authors

A. M. Biedermann· 1 shared C. A. Naranjo· 1 shared C. A. Whittaker· 1 shared H. D. Rao· 1 shared J. C. Love· 1 shared L. E. Crowell· 1 shared M. K. Tracey· 1 shared M. P. Rajurkar· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

A. M. Biedermann

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1 paper

Recent·Most cited

Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor binding domain in engineered Komagataella phaffii

N. C. Dalvie, A. M. Biedermann, S. A. Rodriguez-Aponte, C. A. Naranjo, H. D. Rao, M. P. Rajurkar, R. R. Lothe, U. S. Shaligram, R. S. Johnston, L. E. Crowell, S. Castelino, M. K. Tracey, C. A. Whittaker, J. C. Love

This paper describes an engineered Komagataella phaffii strain for methanol-free production of SARS-CoV-2 RBD, achieving a 5x increase in secreted titer and enabling scalable manufacturing for vaccine development.

bioRxiv · Apr 15, 2021Bioengineering