Author

S. K. Wideman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

A. E. Armitage· 3 shared A. E. Preston· 3 shared J. N. Frost· 3 shared N. White· 3 shared F. C. Richter· 2 shared H. Drakesmith· 2 shared M. R. Teh· 2 shared A. Clarke· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

A. E. Armitage

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ancient genomic linkage couples metabolism with erythroid development

A. E. Preston, J. N. Frost, M. Badat, M. Teh, A. E. Armitage, R. Norfo, S. K. Wideman, M. Hanifi, N. White, N. Roy, B. Ghesquiere, C. Babbs, M. Kassouf, J. Davies, J. Hughes, , H. Drakesmih

This study identifies Nprl3 as a key regulator of erythroid metabolism, showing its role in coupling metabolic and developmental processes during erythropoiesis.

bioRxiv · Sep 25, 2023 · PreprintCell Biology

Cellular iron governs the host response to malaria

S. K. Wideman, J. N. Frost, F. C. Richter, C. Naylor, J. M. Lopes, N. Viveiros, M. R. Teh, A. E. Preston, N. White, S. Yusuf, S. Draper, A. E. Armitage, T. L. Duarte, H. Drakesmith

This study shows that host cell iron scarcity inhibits immune response but reduces liver damage during malaria infection.

bioRxiv · Feb 5, 2023Immunology

Plasma iron controls neutrophil production and function

J. N. Frost, S. K. Wideman, A. E. Preston, M. R. Teh, Z. Ai, L. Wang, A. Cross, N. White, Y. Yazicioglu, M. Bonadonna, A. Clarke, A. E. Armitage, B. Galy, I. A. Udalova, H. Drakesmith

The paper shows hypoferremia reduces neutrophil production and alters their function, while increasing NETosis, and suggests targeting hepcidin could modulate innate immunity.

bioRxiv · Mar 17, 2022Immunology

Adipocyte autophagy limits gut inflammation by controlling oxylipin levels

F. C. Richter, M. Friedrich, N. Kampschulte, M. Pohin, G. Alsaleh, I. Guschina, S. K. Wideman, E. Johnson, M. Borsa, K. Piletic, P. Hahn, H. S. Schipper, C. Edwards, R. Zechner, N. H. Schebb, , A. K. Simon

The paper shows that adipocyte autophagy reduces gut inflammation by regulating oxylipin levels through NRF2-mediated Ephx1 upregulation.

bioRxiv · Oct 25, 2021Immunology