Author

A. E. Preston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. E. Armitage· 4 shared J. N. Frost· 4 shared H. Drakesmith· 3 shared M. R. Teh· 3 shared N. White· 3 shared S. K. Wideman· 3 shared A. Clarke· 1 shared A. Cross· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

A. E. Armitage

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Iron deficiency causes aspartate-sensitive metabolic and proliferative dysfunction in CD8+ T cells

M. R. Teh, N. Gudgeon, J. N. Frost, L. V. Sinclair, A. L. Smith, C. L. Millington, B. Kronsteiner, J. Roberts, B. P. Marzullo, A. E. Preston, J. Rehwinkel, T. A. Milne, D. A. Tennant, S. J. Dunachie, A. E. Armitage, , H. Drakesmith

This study shows iron deficiency impairs CD8+ T cell proliferation and metabolism by disrupting mitochondrial function, but exogenous aspartate can rescue this defect.

bioRxiv · Feb 1, 2024 · PreprintImmunology

Ancient genomic linkage couples metabolism with erythroid development

A. E. Preston, J. N. Frost, M. Badat, M. Teh, A. E. Armitage, R. Norfo, S. K. Wideman, M. Hanifi, N. White, N. Roy, B. Ghesquiere, C. Babbs, M. Kassouf, J. Davies, J. Hughes, , H. Drakesmih

This study identifies Nprl3 as a key regulator of erythroid metabolism, showing its role in coupling metabolic and developmental processes during erythropoiesis.

bioRxiv · Sep 25, 2023 · PreprintCell Biology

Cellular iron governs the host response to malaria

S. K. Wideman, J. N. Frost, F. C. Richter, C. Naylor, J. M. Lopes, N. Viveiros, M. R. Teh, A. E. Preston, N. White, S. Yusuf, S. Draper, A. E. Armitage, T. L. Duarte, H. Drakesmith

This study shows that host cell iron scarcity inhibits immune response but reduces liver damage during malaria infection.

bioRxiv · Feb 5, 2023Immunology

Plasma iron controls neutrophil production and function

J. N. Frost, S. K. Wideman, A. E. Preston, M. R. Teh, Z. Ai, L. Wang, A. Cross, N. White, Y. Yazicioglu, M. Bonadonna, A. Clarke, A. E. Armitage, B. Galy, I. A. Udalova, H. Drakesmith

The paper shows hypoferremia reduces neutrophil production and alters their function, while increasing NETosis, and suggests targeting hepcidin could modulate innate immunity.

bioRxiv · Mar 17, 2022Immunology