Author

T. Look

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

M. Zenke· 2 shared Z. Li· 2 shared A. Schippers· 1 shared A. Yang· 1 shared B. Denecke· 1 shared B. J. Pinch· 1 shared B. Lambrecht· 1 shared B. Nabet· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

M. Zenke

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CREB REGULATES FOXP3+ST-2+ TREGS WITH ENHANCED IL-10 PRODUCTION

S. Hebbar Subramanyam, J. Hriczko, S. Schulz, T. Look, T. Goodarzi, T. Clarner, M. Scheld, M. Kipp, E. Verjans, S. Boell, C. Neullens, I. Costa, Z. Li, L. Gan, B. Denecke, , K. Tenbrock

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

bioRxiv · Jun 29, 2024Immunology

A lncRNA identifies IRF8 enhancer element in negative feedback control of dendritic cell differentiation

H. Xu, Z. Li, C.-C. Kuo, K. Goetz, T. Look, M. A. Szymanski de Toledo, K. Sere, I. Gesteira Costa Filho, M. Zenke

The paper identifies a long non-coding RNA that regulates IRF8 autoactivation through a negative feedback loop in dendritic cell differentiation.

bioRxiv · Aug 11, 2022Cell Biology

Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivo

C. Dubiella, B. J. Pinch, D. Zaidman, T. D. Manz, E. Poon, S. He, E. Resnick, E. M. Langer, C. J. Daniel, H.-S. Seo, Y. Chen, S. B. Ficarro, Y. Jamin, X. Lian, S. Kibe, , N. London

Sulfopin, a selective Pin1 inhibitor, reduces tumor initiation and growth in neuroblastoma models by targeting c-Myc pathways.

bioRxiv · Mar 20, 2020 · PreprintCancer Biology