Author

S. G. Clarke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Evans-Molina· 1 shared C. F. Clarke· 1 shared C. Speake· 1 shared E. A. James· 1 shared I. Endo· 1 shared J. Kanyo· 1 shared J. Yamamoto· 1 shared K. C. Herold· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

C. Evans-Molina

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Author profile →

2 papers

Recent·Most cited

Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity

M.-L. Yang, S. Connolly, R. Gee, T. Lam, J. Kanyo, S. G. Clarke, C. F. Clarke, E. A. James, C. Speake, C. Evans-Molina, L. Wen, K. C. Herold, M. Mamula

The paper identifies carbonylated P4Hb as an autoantigen in type 1 diabetes, detected before hyperglycemia in NOD mice and early human disease.

bioRxiv · Jun 15, 2021 · PreprintImmunology

The linkage of methionine addiction, overmethylation of histone H3 lysines and malignancy demonstrated when cancer cells revert to methionine-independence

J. Yamamoto, S. Inubushi, Q. Han, Y. Tashiro, N. Sugisawa, K. Hamada, Y. Aoki, K. Miyake, R. Matsuyama, M. Bouvet, S. G. Clarke, I. Endo, R. M. Hoffman

The paper shows that methionine-independent cancer cell revertants have reduced histone H3 lysine trimethylation and lower tumorigenicity and metastatic potential compared to methionine-addicted parental cells.

bioRxiv · Dec 4, 2020 · PreprintCancer Biology