Author

S. G. Drakos

University of Utah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

C. H. Selzman· 2 shared D. Chaudhuri· 2 shared T. S. Shankar· 2 shared A. A. Cluntun· 1 shared A. M. Balynas· 1 shared Aiora Martinez-Vilchez· 1 shared Ann-Katrin M. Pfeuffer· 1 shared C. P. Kyriakopoulos· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

C. H. Selzman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PKC Promotes T-Tubule Membrane Loss by Activating a PKD-NFκB Endocytic Pathway

Aiora Martinez-Vilchez, Ann-Katrin M. Pfeuffer, Janna Sophie Wessolowski, Dominik J. Fiegle, Philipp Andrae, Prapassorn Potue, L. K. Küpfer, Thirupura Sundari Shankar, C. H. Selzman, S. G. Drakos, Christian Heim, Tilmann Volk, Thomas Seidel

This study identifies PKC-driven T-tubule membrane loss through a PKD-NFκB endocytic pathway in cardiomyocytes, showing impaired contractility and arrhythmia risk.

bioRxiv · May 4, 2025 · PreprintCell Biology

Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.

J. R. Visker, A. A. Cluntun, J. N. Velasco-Silva, D. R. Eberhardt, T. S. Shankar, R. Hamouche, J. Ling, H. Kwak, Y. Hillas, I. Aist, E. Tseliou, S. Navankasattusas, D. Chaudhuri, G. S. Ducker, S. G. Drakos, J. Rutter

This study shows that inhibiting MCT4 to redirect pyruvate metabolism reduces myocardial ischemia-reperfusion injury by improving mitochondrial function and reducing oxidative stress.

bioRxiv · Feb 1, 2024 · PreprintPhysiology

Mitochondria possess a large, non-selective ionic current that is enhanced during cardiac injury.

E. Balderas, S. H. J. Lee, T. S. Shankar, X. Yin, A. M. Balynas, C. P. Kyriakopoulos, C. H. Selzman, S. G. Drakos, D. Chaudhuri

The paper identifies a large, non-selective ionic current in mitochondria, called LUNA, which increases during cardiac injury and is inhibited by amiloride.

bioRxiv · Nov 15, 2023 · PreprintCell Biology