Author

T. S. Shankar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. Chaudhuri· 2 shared S. G. Drakos· 2 shared A. A. Cluntun· 1 shared A. M. Balynas· 1 shared C. H. Selzman· 1 shared C. P. Kyriakopoulos· 1 shared D. R. Eberhardt· 1 shared E. Balderas· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

D. Chaudhuri

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2 papers

Recent·Most cited

Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.

J. R. Visker, A. A. Cluntun, J. N. Velasco-Silva, D. R. Eberhardt, T. S. Shankar, R. Hamouche, J. Ling, H. Kwak, Y. Hillas, I. Aist, E. Tseliou, S. Navankasattusas, D. Chaudhuri, G. S. Ducker, S. G. Drakos, J. Rutter

This study shows that inhibiting MCT4 to redirect pyruvate metabolism reduces myocardial ischemia-reperfusion injury by improving mitochondrial function and reducing oxidative stress.

bioRxiv · Feb 1, 2024 · PreprintPhysiology

Mitochondria possess a large, non-selective ionic current that is enhanced during cardiac injury.

E. Balderas, S. H. J. Lee, T. S. Shankar, X. Yin, A. M. Balynas, C. P. Kyriakopoulos, C. H. Selzman, S. G. Drakos, D. Chaudhuri

The paper identifies a large, non-selective ionic current in mitochondria, called LUNA, which increases during cardiac injury and is inhibited by amiloride.

bioRxiv · Nov 15, 2023 · PreprintCell Biology