Author

S. H. Sternberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:genome assembly· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Yildiz· 2 shared J. A. Doudna· 2 shared J. S. Chen· 2 shared Y. S. Dagdas· 2 shared B. P. Kleinstiver· 1 shared C. Ronda· 1 shared D. R. Gelsinger· 1 shared H. H. Wang· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. Yildiz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bacterial genome engineering using CRISPR RNA-guided transposases

D. R. Gelsinger, P. L. H. Vo, S. E. Klompe, C. Ronda, H. H. Wang, S. H. Sternberg

This paper describes a CRISPR RNA-guided transposase system for efficient bacterial genome engineering, including a computational tool for crRNA design and a protocol for multiplexed DNA insertion.

bioRxiv · Mar 18, 2023Bioengineering

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

J. S. Chen, Y. S. Dagdas, B. P. Kleinstiver, M. M. Welch, L. B. Harrington, S. H. Sternberg, J. K. Joung, A. Yildiz, J. A. Doudna

This study identifies a mechanism by which CRISPR-Cas9 variants discriminate target mismatches and introduces a hyper-accurate variant with improved specificity.

bioRxiv · Aug 12, 2017Biochemistry

A Conformational Checkpoint Between DNA Binding And Cleavage By CRISPR-Cas9

Y. S. Dagdas, J. S. Chen, S. H. Sternberg, J. A. Doudna, A. Yildiz

This study identifies a conformational checkpoint in CRISPR-Cas9 that regulates DNA cleavage by requiring divalent cations and preventing cleavage at off-target sites with sequence mismatches.

bioRxiv · Mar 30, 2017Biophysics