Author

S. Ishiguro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

H. Aburatani· 2 shared N. Yachie· 2 shared A. Kondo· 1 shared A. Tsubouchi· 1 shared H. Mori· 1 shared H. Nishimasu· 1 shared K. Nishida· 1 shared K. Teranishi· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

H. Aburatani

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Author profile →

2 papers

Recent·Most cited

Pooled CRISPR screening of high-content cellular phenotypes by ghost cytometry

A. Tsubouchi, Y. An, Y. Kawamura, Y. Yanagihashi, Y. Murata, K. Teranishi, S. Ishiguro, H. Aburatani, N. Yachie, S. Ota

The paper introduces a ghost cytometry-based method for fast pooled CRISPR screening of high-content cellular phenotypes, including fluorescence and label-free modes, enabling genome-wide analysis of gene effects on cellular processes.

bioRxiv · Jan 26, 2023 · PreprintCell Biology

A single CRISPR base editor to induce simultaneous C-to-T and A-to-G mutations

R. C. Sakata, S. Ishiguro, H. Mori, M. Tanaka, M. Seki, N. Masuyama, K. Nishida, H. Nishimasu, A. Kondo, O. Nureki, M. Tomita, H. Aburatani, N. Yachie

This paper introduces Target-ACE, a CRISPR base editor that induces both C-to-T and A-to-G mutations, showing higher efficiency than using separate editors.

bioRxiv · Aug 8, 2019 · PreprintBioengineering