Author

H. Aburatani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

N. Yachie· 2 shared S. Ishiguro· 2 shared A. Kondo· 1 shared A. Okamoto· 1 shared A. Tsubouchi· 1 shared C. G. Proud· 1 shared C. Zorbas· 1 shared D. L. Lafontaine· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

N. Yachie

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pooled CRISPR screening of high-content cellular phenotypes by ghost cytometry

A. Tsubouchi, Y. An, Y. Kawamura, Y. Yanagihashi, Y. Murata, K. Teranishi, S. Ishiguro, H. Aburatani, N. Yachie, S. Ota

The paper introduces a ghost cytometry-based method for fast pooled CRISPR screening of high-content cellular phenotypes, including fluorescence and label-free modes, enabling genome-wide analysis of gene effects on cellular processes.

bioRxiv · Jan 26, 2023 · PreprintCell Biology

Tandemly repeated genes promote RNAi-mediated heterochromatin formation via an anti-silencing factor Epe1 in fission yeast

T. Asanuma, S. Inagaki, T. Kakutani, H. Aburatani, Y. Murakami

bioRxiv · Jul 4, 2022 · PreprintBiochemistry

Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

M. Pan, C. Zorbas, M. Sugaya, K. Ishiguro, M. Kato, M. Nishida, H. Zhang, M. M. Candeias, A. Okamoto, T. Ishikawa, T. Soga, H. Aburatani, J. Sakai, Y. Matsumura, T. Suzuki, , T. Osawa

The paper shows that glutamine deficiency in cancer cells prevents p53 activation by rRNA synthesis inhibitors, promoting survival during nutrient stress.

bioRxiv · Dec 3, 2021 · PreprintCancer Biology

A single CRISPR base editor to induce simultaneous C-to-T and A-to-G mutations

R. C. Sakata, S. Ishiguro, H. Mori, M. Tanaka, M. Seki, N. Masuyama, K. Nishida, H. Nishimasu, A. Kondo, O. Nureki, M. Tomita, H. Aburatani, N. Yachie

This paper introduces Target-ACE, a CRISPR base editor that induces both C-to-T and A-to-G mutations, showing higher efficiency than using separate editors.

bioRxiv · Aug 8, 2019 · PreprintBioengineering