Y. Murata

Patient phenotypes and their relation to TNFα signaling and immune cell composition in critical illness and autoimmune disease

The paper identifies a hyper-inflammatory phenotype linked to TNF signaling and mature neutrophils in critical illness and autoimmune disease using machine learning and patient data.

Coordinated regulation of gene expression in Plasmodium female gametocytes by two transcription factors

This study identifies a novel transcription factor, PFG, that cooperates with AP2-FG to regulate gene expression in Plasmodium female gametocytes, affecting ookinete formation and gene activation.

Pooled CRISPR screening of high-content cellular phenotypes by ghost cytometry

The paper introduces a ghost cytometry-based method for fast pooled CRISPR screening of high-content cellular phenotypes, including fluorescence and label-free modes, enabling genome-wide analysis of gene effects on cellular processes.

The stoichiometric interaction model for mesoscopic molecular dynamics simulations of liquid-liquid phase separation

This paper introduces a new potential, the stoichiometric interaction potential, to improve mesoscopic simulations of liquid-liquid phase separation in multidomain proteins, achieving quantitative agreement with experimental data.

Targetome analysis of malaria sporozoite transcription factor AP2-Sp reveals its role as a master regulator

The paper identifies AP2-Sp target genes in malaria sporozoites, revealing its role as a master regulator through transcriptional auto-activation and regulation of other TFs.