Author

S. J. Chen

University of Groningen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. P. Liu· 2 shared G. Cai· 2 shared S.-S. Lin· 2 shared A. Celli· 1 shared A. Honkala· 1 shared A. W. Brooks· 1 shared B. A. Yang· 1 shared B.-Y. Hong· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

A. P. Liu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Modeling disorder, secondary structure formation, and amyloid growth in FG-nucleoporins

Maurice Dekker, S. J. Chen, Vasista Adupa, Patrick R. Onck

This paper introduces a computational model to simulate the dual behavior of FG-nucleoporins between disordered and fibrillar states, showing their ability to form condensates and amyloid-like structures.

bioRxiv · Apr 8, 2026 · PreprintBiophysics

Cellular mechanotransduction of human osteoblasts in microgravity

N. H. Wubshet, G. Cai, S. J. Chen, M. Sullivan, M. Reeves, D. Mays, M. Harrison, P. Varnado, B. A. Yang, E. Arreguin-Martinez, Y. Qu, S.-S. Lin, P. Duran, C. A. Aguilar, S. Giza, , A. P. Liu

This study investigates how microgravity affects human fetal osteoblasts by measuring cell mechanics and signaling changes in space compared to ground controls.

bioRxiv · Mar 3, 2024Cell Biology

Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

X. Zhou, X. Shen, J. Johnson, D. Spakowicz, M. Agnello, W. Zhou, M. Avina, A. Honkala, F. Chleilat, S. J. Chen, K. Cha, S. Leopold, C. Zhu, L. Chen, L. Lyu, , M. P. Snyder

This study tracks microbiome changes across four body sites in 86 participants over six years, revealing site-specific stability, individualized dynamics, and altered patterns in insulin-resistant individuals.

bioRxiv · Feb 1, 2024Microbiology

Matrix confinement modulates 3D spheroid sorting and burst-like collective migration

G. Cai, X. Li, S.-S. Lin, S. J. Chen, N. C. Rodgers, K. M. Koning, D. Bi, A. P. Liu

This study shows that matrix confinement affects 3D spheroid sorting and collective migration, with sorting dependent on cell-cell adhesion and matrix resistance.

bioRxiv · Jul 23, 2023Biophysics