Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing
N. Frey, L. Tortola, D. Egli, S. Janjuha, K. F. Marquart, T. Rothgangl, F. Ampenberger, M. Kopf, G. Schwank
This study identifies Rnf31 and Vps4b as factors enabling pancreatic cancer to evade T cell killing, showing their inactivation increases T cell-mediated tumor cell death.
bioRxiv · Jul 29, 2021Cancer Biology