Author

S. Karunakaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

B. Bothner· 1 shared C. L. K. Leung· 1 shared D. M. Fialho· 1 shared E. Antony· 1 shared G. B. Schuster· 1 shared I. Martinez· 1 shared J. D. Johnson· 1 shared J. Deveryshetty· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

B. Bothner

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3 papers

Recent·Most cited

Homodecameric Rad52 promotes single-position Rad51 nucleation in homologous recombination

J. Deveryshetty, R. Chadda, J. Mattice, S. Karunakaran, M. Rau, K. Basore, N. Pokhrel, N. Englander, J. Fitzpatrick, B. Bothner, E. Antony

This study reveals that homodecameric Rad52 facilitates single-position Rad51 nucleation in homologous recombination through specific structural and interaction features.

bioRxiv · Feb 5, 2023 · PreprintBiochemistry

Analysis of a genetic region affecting mouse body weight

C. L. K. Leung, S. Karunakaran, M. G. Atser, L. Innala, X. Hu, V. Viau, J. D. Johnson, S. M. Clee

This study investigates genetic factors affecting obesity in mice, identifying a region on chromosome 2 and exploring the role of Pdk1 and Itga6 in obesity and glucose metabolism.

bioRxiv · Aug 24, 2022Physiology

Depsipeptide nucleic acids: prebiotic formation, oligomerization, and self-assembly of a new candidate proto-nucleic acid

N. V. Hud, D. M. Fialho, S. Karunakaran, K. W. Greeson, I. Martinez, G. B. Schuster, R. Krishnamurthy

This study introduces depsipeptide nucleic acid as a prebiotic candidate for the first informational polymer, showing its spontaneous formation and self-assembly under plausible early Earth conditions.

bioRxiv · Sep 1, 2020Biochemistry