S. Kelley

The O-Fucosyltransferase SPINDLY Attenuates Auxin-Induced Fruit Growth by Inhibiting ARF6 and ARF8 binding to Coactivator Mediator Complex in Arabidopsis

This study shows that SPINDLY-mediated O-fucosylation of ARF6 and ARF8 inhibits their interaction with the coactivator Mediator complex, reducing fruit growth in Arabidopsis.

Endothelial Drp1 Couples VEGF-induced Redox Signaling with Glycolysis Through Cysteine Oxidation to Drive Angiogenesis

Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic Reprograming

This study shows that myeloid Drp1 deficiency impairs revascularization in ischemic muscle by promoting pro-inflammatory macrophage polarization and metabolic reprogramming.

Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis

This study identifies SLIT2 as a regulator of metastasis through a genome-wide CRISPR screen of circulating tumor cells in a mouse model.

Reagentless Biomolecular Analysis Using a Nanoscale Molecular Pendulum

This paper introduces a reagentless sensor that detects molecular analytes in biological fluids by measuring directional diffusion of a nanoscale molecular pendulum and electron-transfer kinetics.

Results dissemination from clinical trials conducted at German university medical centres was delayed and incomplete

The paper tracks results dissemination from clinical trials at German university medical centers, finding delays and incomplete reporting.

Exposure to a Healthy Gut Microbiome Protects Against Reproductive and Metabolic Dysregulation in a PCOS Mouse Model

This study shows that co-housing PCOS mice with healthy mice improves reproductive and metabolic PCOS symptoms, suggesting gut microbiome manipulation could be a treatment.