Author

S. Korolchuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

J. A. Endicott· 2 shared J. R. Ault· 2 shared M. Salamina· 2 shared A. al-Rawi· 1 shared A. Basle· 1 shared B. C. Montefiore· 1 shared D. J. Wood· 1 shared F. Sobott· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

J. A. Endicott

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Author profile →

3 papers

Recent·Most cited

Cryo-EM structure of the CDK2-cyclin A-CDC25A complex

R. J. Rowland, S. Korolchuk, M. Salamina, J. R. Ault, S. Hart, J. P. Turkenberg, J. N. Blaza, M. E. Noble, J. A. Endicott

The paper presents the cryo-EM structure of the CDK2-cyclin A-CDC25A complex, revealing key interactions and suggesting potential binding partners for CDC25A.

bioRxiv · Oct 17, 2023 · PreprintBiochemistry

Cyclin A and Cks1 promote kinase consensus switching to non-proline directed CDK1 phosphorylation

A. al-Rawi, S. Korolchuk, J. Endicott, T. Ly

The paper shows Cyclin A and Cks1 enable CDK1 to phosphorylate non-proline directed sites, particularly with a +3 lysine residue, altering substrate choice based on CDK1 activity.

bioRxiv · May 24, 2022Biochemistry

Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation

M. Salamina, B. C. Montefiore, M. Liu, D. J. Wood, R. Heath, J. R. Ault, L.-Z. Wang, S. Korolchuk, A. Basle, M. W. Pastok, J. Reeks, N. J. Tatum, F. Sobott, S. T. Arold, M. Pagano, , J. A. Endicott

The paper identifies a cyclin A-specific interaction between SKP2 and CDK2-cyclin A complexes that promotes p27KIP1 degradation, distinguishing cyclin A from other G1 cyclins.

bioRxiv · Oct 8, 2020Biochemistry