Author

J. R. Ault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

F. Sobott· 2 shared J. A. Endicott· 2 shared M. Salamina· 2 shared S. Korolchuk· 2 shared A. Basle· 1 shared A. C. Kalli· 1 shared A. N. Calabrese· 1 shared B. C. Montefiore· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

F. Sobott

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3 papers

Recent·Most cited

Cryo-EM structure of the CDK2-cyclin A-CDC25A complex

R. J. Rowland, S. Korolchuk, M. Salamina, J. R. Ault, S. Hart, J. P. Turkenberg, J. N. Blaza, M. E. Noble, J. A. Endicott

The paper presents the cryo-EM structure of the CDK2-cyclin A-CDC25A complex, revealing key interactions and suggesting potential binding partners for CDC25A.

bioRxiv · Oct 17, 2023 · PreprintBiochemistry

Tension mediated mechanical activation and pocket delipidation lead to an analogous MscL state

B. Wang, B. J. Lane, C. Kapsalis, J. R. Ault, F. Sobott, H. El Mkami, A. N. Calabrese, A. C. Kalli, C. Pliotas

This study investigates how tension and pocket delipidation affect MscL channel states, finding they lead to similar expanded states but through different pathways.

bioRxiv · Apr 1, 2021 · PreprintBiophysics

Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation

M. Salamina, B. C. Montefiore, M. Liu, D. J. Wood, R. Heath, J. R. Ault, L.-Z. Wang, S. Korolchuk, A. Basle, M. W. Pastok, J. Reeks, N. J. Tatum, F. Sobott, S. T. Arold, M. Pagano, , J. A. Endicott

The paper identifies a cyclin A-specific interaction between SKP2 and CDK2-cyclin A complexes that promotes p27KIP1 degradation, distinguishing cyclin A from other G1 cyclins.

bioRxiv · Oct 8, 2020Biochemistry