Author

S. Kugel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. C. Holland· 2 shared F. Szulzewsky· 2 shared J. G. Henikoff· 2 shared K. Ahmad· 2 shared R. M. Paranal· 2 shared S. Henikoff· 2 shared Z. R. Russell· 2 shared C. M. Ferrer· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

E. C. Holland

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3 papers

Recent·Most cited

RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples

S. Henikoff, Y. Zheng, R. M. Paranal, Y. Xu, J. E. Greene, J. G. Henikoff, Z. R. Russell, F. Szulzewsky, H. N. Thirimanne, S. Kugel, E. C. Holland, K. Ahmad

The paper identifies RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples, linking it to tumor progression and aneuploidy.

bioRxiv · Feb 28, 2024Cancer Biology

Epigenomic analysis of Formalin-Fixed Paraffin-Embedded samples by CUT&Tag

S. Henikoff, J. G. Henikoff, K. Ahmad, R. M. Paranal, D. H. Janssens, Z. R. Russell, F. Szulzewsky, S. Kugel, E. C. Holland

This study modifies the CUTAC protocol to enable high-resolution epigenomic analysis of FFPE samples, identifying regulatory element differences in mouse brain tumors.

bioRxiv · Jun 20, 2023Cancer Biology

The glutathione S-transferase Gstt1 is a robust driver of survival and dissemination in metastases

C. M. Ferrer, R. Boon, H. Cho, T. Bernasocchi, L. P. Wong, M. Cetinbas, E. R. Haggerty, I. Mitsiades, G. R. Wojtkiewicz, D. E. McLoughlin, S. Kugel, E. Rheinbay, R. Sadreyev, D. Juric, R. Mostoslavsky

This study identifies Gstt1 as a critical driver of metastasis and dissemination in pancreatic cancer, showing its role in maintaining metastatic lesions and influencing the tumor microenvironment.

bioRxiv · Sep 10, 2022 · PreprintCancer Biology