Author

S. L. O'Brien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Calebiro· 2 shared A. Boufersaoui· 1 shared A. K. Shukla· 1 shared B. D. Hudson· 1 shared B. Medel-Lacruz· 1 shared D. A. Tennant· 1 shared D. M. Owen· 1 shared E. Tripp· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

D. Calebiro

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets

D. Calebiro, S. L. O'Brien, E. Tripp, G. Smith, A. Boufersaoui, J. Roberts, J. A. Pike, J. Correia, T. A. Miljus, D. A. Tennant, B. D. Hudson, G. Milligan, Z. Gerhart-Hines, T. W. Schwartz

The paper shows FFA4, a GPCR, signals from lipid droplet-associated membranes in adipocytes, providing localized feedback to regulate lipolysis.

bioRxiv · Jul 28, 2023 · PreprintPharmacology & Toxicology

Single-molecule analysis of receptor-beta-arrestin interactions in living cells

J. Grimes, Z. Koszegi, Y. Lanoiselee, T. Miljus, S. L. O'Brien, T. M. Stepniewski, B. Medel-Lacruz, M. Baidya, M. Makarova, D. M. Owen, A. K. Shukla, J. Selent, S. J. Hill, D. Calebiro

This study uses single-molecule microscopy and simulations to show that beta-arrestin inserts into the lipid bilayer and interacts with receptors through lateral diffusion, challenging existing models of its function.

bioRxiv · Nov 15, 2022 · PreprintCell Biology