Author

S. M. Guldberg

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Y. Nabet· 1 shared D. A. Dillon· 1 shared E. J. Kim· 1 shared F. Lynce· 1 shared I. Tenvooren· 1 shared J. L. Yee· 1 shared J. M. Rosenbluth· 1 shared J. Z. Yu· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

B. Y. Nabet

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1 paper

Recent·Most cited

T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFa Inflammation.

N. W. Cho, S. M. Guldberg, B. Y. Nabet, J. Z. Yu, E. J. Kim, K. J. Hiam-Galvez, J. L. Yee, R. DeBarge, I. Tenvooren, N. A. Ashitey, F. Lynce, D. A. Dillon, J. M. Rosenbluth, M. H. Spitzer

The paper identifies a novel mechanism of ICI resistance where T cells drive inflammatory resistance via IL-1 and TNF in tumors, with implications for therapy.

bioRxiv · Sep 20, 2022Immunology