K. J. Hiam-Galvez

This study identifies two molecular groups in schwannomas driven by epigenetic reprogramming and shows ionizing radiation can reprogram neural crest to immune-enriched schwannomas.

This study shows that commensal microbes in neonatal skin promote immune homeostasis by regulating monocyte accumulation and IL-17A production by T cells.

The paper identifies a novel mechanism of ICI resistance where T cells drive inflammatory resistance via IL-1 and TNF in tumors, with implications for therapy.

This study identifies divergent clonal differentiation trajectories of T cell exhaustion during chronic viral infection, showing that TCR signal strength determines terminal or KLR Tex fates.

The paper shows that transient dendritic cell activation during acute infection shapes T cell fate by timing their priming and influencing whether they become effector or memory cells.

The paper identifies that severe COVID-19 patients lack ISG-expressing cells and have antibodies that block their production, contrasting with mild cases.