S. Moreira

A two-step in vivo CRISPR screen unveils pervasive RNA binding protein dependencies for leukemic stem cells and identifies ELAVL1 as a therapeutic target

This study identifies RNA binding proteins essential for leukemic stem cell survival using an in vivo CRISPR screen and highlights ELAVL1 as a therapeutic target in AML.

SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-weeks interval between doses

This study evaluates how plasma from individuals with a 16-week interval between BNT162b2 mRNA vaccine doses recognizes and neutralizes the Omicron Spike compared to other variants.

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

This study investigates how temperature affects SARS-CoV-2 Spike protein affinity for ACE2, finding increased binding at low temperatures, which is mitigated by the N501Y mutation.

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

This study shows a single dose of the BNT162b2 mRNA vaccine elicits strong antibody and T cell responses, including Fc-mediated effector functions, and boosts pre-existing immunity in previously infected individuals.

Comparison Between Normobaric Hypoxia Altitude Simulation Test and Altitude Hypoxia Predictive Equations in Cystic Fibrosis Patients

The paper compares normobaric hypoxia altitude simulation test results with five predictive equations in cystic fibrosis patients to assess their accuracy in predicting in-flight hypoxia.

TCF7L1 and TCF7 differentially regulate specific mouse ES cell genes in response to GSK-3 inhibition

This study shows TCF7L1 and TCF7 have distinct chromatin occupancy patterns in mouse ES cells, with TCF7L1 binding more genes and showing target-specific modulation by GSK-3 inhibition.

Endogenous BioID elucidates TCF7L1 interactome modulation upon GSK-3 inhibition in mouse ESCs

The paper uses BioID to study TCF7L1 interactome changes in mouse ESCs with GSK-3 inhibition, identifying new interactors and showing increased detection with reduced BirA*-TCF7L1 levels.

Anthropometric and functional profiles of elite athletes from different categories at ABADA Capoeira World Championship

This study analyzes the anthropometric and functional profiles of male elite Capoeira athletes across weight categories to identify somatotype and performance differences.