Author

S. Nikolaou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

L. Fort· 3 shared J. A. Whitelaw· 2 shared L. M. Machesky· 2 shared N. R. Paul· 2 shared A. H. Le· 1 shared A. Juin· 1 shared C. Nixon· 1 shared H. J. Spence· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

L. Fort

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge

J. A. Whitelaw, S. Lilla, S. Nikolaou, L. Tweedy, L. Fort, N. R. Paul, S. Zanivan, N. Gadegaard, R. H. Insall, L. M. Machesky

bioRxiv · Mar 26, 2024Cell Biology

CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

S. Nikolaou, A. Juin, J. A. Whitelaw, N. R. Paul, L. Fort, C. Nixon, H. J. Spence, S. Bryson, L. M. Machesky

The paper identifies CYRI-B as a mediator of macropinocytosis in pancreatic cancer, showing it suppresses metastasis by enabling lysophosphatidic acid receptor uptake.

bioRxiv · Nov 23, 2022Cancer Biology

CYRI-A regulates macropinocytic cup maturation and mediates integrin uptake, limiting invasive migration

A. H. Le, T. Yelland, N. Paul, L. Fort, S. Nikolaou, S. Ismail, L. Machesky

This study identifies CYRI-A as a regulator of macropinocytic cup maturation and integrin uptake, showing its role in limiting invasive migration.

bioRxiv · Dec 4, 2020Cell Biology