Author

S. P. Blagden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

H. Schwenzer· 2 shared A. A. Ahmed· 1 shared A. Coosemans· 1 shared A. Easton· 1 shared A. L. Harris· 1 shared A. Protheroe· 1 shared A. Ryan· 1 shared B. Kessler· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

H. Schwenzer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LARP1 regulates metabolism and mTORC1 activity in cancer

J. Chettle, Z. Dedeic, R. Fischer, I. Vendrell, L. Campo, A. Easton, M. Browne, J. Morris, H. Schwenzer, P. Lascaux, R. Gijsbers, E. Pires, D. J. Royston, D. J. P. Ferguson, A. Coosemans, , S. P. Blagden

This study identifies LARP1 as a key regulator of metabolism and mTORC1 activity in cancer, showing its role in sustaining cellular metabolism and driving cancer progression.

bioRxiv · Sep 4, 2022 · PreprintCancer Biology

Subcellular mRNA localization regulates ribosome biogenesis in migrating cells

M. Dermit, M. Dodel, F. C. Y. Lee, M. S. Azman, H. Schwenzer, J. L. Jones, S. P. Blagden, J. Ule, F. K. Mardakheh

The paper shows that subcellular localization of RP-mRNAs via LARP6 enhances ribosome biogenesis during cell migration and supports cancer progression through EMT.

bioRxiv · Dec 2, 2019Cell Biology

Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression and drug response

P. Zhang, I. Kitchen-Smith, L. Xiong, G. Stracquadanio, K. Brown, P. Richter, M. Wallace, E. Bond, N. Sahgal, S. Moore, S. Nornes, S. De Val, M. Surakhy, D. Sims, X. Wang, , G. Bond

The paper investigates interactions between germline and somatic variants in the p53 pathway to show their combined effects on cancer risk, progression, and treatment response.

bioRxiv · Nov 9, 2019Cancer Biology