Author

S. P. Colgan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. A. Steiner· 2 shared C. H. Hall· 2 shared E. M. Murphy· 2 shared I. M. Cartwright· 2 shared L. Zhou· 2 shared A. L. Theiss· 1 shared A. S. Dowdell· 1 shared A. W. Staley· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

C. A. Steiner

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner

R. C. Callahan, J. C. Curry, G. Bhagavatula, A. W. Staley, R. E. M. Schaefer, F. Minhajuddin, L. Zhou, R. M. Neuhart, S. M. Atif, D. J. Orlicky, I. M. Cartwright, M. E. Gerich, C. A. Steiner, A. L. Theiss, C. H. T. Hall, , J. C. Onyiah

This study shows that epithelial HO-1 promotes colonic tumorigenesis in chronic inflammation by increasing iron availability and oxidative stress, while protecting against acute heme toxicity.

bioRxiv · Mar 6, 2024Cancer Biology

Fundamental role for the creatine kinase pathway in protection from murine colitis

C. H. Hall, J. M. Lanis, A. S. Dowdell, E. M. Murphy, S. P. Colgan

This study shows that creatine kinase pathway loss increases susceptibility to colitis by reducing IFN-γ production in T cells.

bioRxiv · Jun 7, 2023Immunology

Synaptopodin is required for efficient intercellular spread by bacterial pathogens

J. M. Vickery, J. D. Toperzer, J. E. Raab, D. J. Hamilton, T. B. Harju, T. N. Huynh, L. Zhou, L. L. Lenz, S. P. Colgan, B. C. Russo

This study identifies synaptopodin as essential for efficient intercellular spread of Shigella flexneri and Listeria monocytogenes by stabilizing actin tails and enabling protrusion formation.

bioRxiv · Apr 25, 2023 · PreprintMicrobiology

The TNF{blacktriangleup}ARE mouse as a model of intestinal fibrosis

C. A. Steiner, S. D. Koch, T. Evanoff, N. Welch, R. Kostelecky, R. Callahan, E. M. Murphy, C. H. Hall, S. Lu, M. C. Weiser-Evans, I. M. Cartwright, S. P. Colgan

The paper evaluates the TNF{Delta}ARE mouse as a model of intestinal fibrosis, finding it develops structural, histological, and genetic changes of ileal fibrosis by 24 weeks.

bioRxiv · Jan 13, 2023 · PreprintCell Biology

Intense light-mediated circadian cardioprotection via transcriptional reprogramming of the endothelium

Y. Oyama, C. M. Bartman, S. Bonnie, J. S. Lee, L. A. Walker, J. Han, C. H. Borchers, P. M. Buttrick, C. Aherne, N. Clendenen, S. P. Colgan, T. Eckle

This study identifies circadian PER2 amplitude enhancement in endothelial cells as a novel cardioprotective strategy that mimics HIF1A metabolic adaptation during myocardial ischemia.

bioRxiv · Jul 12, 2019Cell Biology