Author

S. Reedtz-Runge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:structural biology· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Christopoulos· 1 shared A. Dai· 1 shared A. Glukhova· 1 shared A. J. Kooistra· 1 shared B. Wu· 1 shared C. He· 1 shared C. J. Langmead· 1 shared C. R. Underwood· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Christopoulos

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2 papers

Recent·Most cited

Structures of the human cholecystokinin receptors in complex with agonists and antagonists

X. Zhang, C. He, M. Wang, Q. zhou, D. Yang, Y. Zhu, W. Feng, H. Zhang, A. Dai, X. Chu, J. Wang, Z. Yang, Y. Jiang, U. Sensfuss, Q. Tan, , Q. Zhao

The paper reports crystal and cryo-EM structures of human CCKAR and CCKBR with ligands, revealing ligand recognition and activation mechanisms.

bioRxiv · May 19, 2021 · PreprintBiophysics

Differential GLP-1R binding and activation by peptide and non-peptide agonists

X. Zhang, M. J. Belousoff, P. Zhao, A. J. Kooistra, T. T. Truong, S. Y. Ang, C. R. Underwood, T. Egebjerg, P. Senel, G. D. Stewart, Y.-L. Liang, A. Glukhova, H. Venugopal, A. Christopoulos, S. G. Furness, , D. Wootten

The paper compares the binding and activation of the GLP-1 receptor by peptide and non-peptide agonists, revealing structural and functional differences that inform drug design.

bioRxiv · Aug 16, 2020Pharmacology & Toxicology