Author

S. S.-Y. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

X. Wang· 2 shared B. M. Wolska· 1 shared D. Jung· 1 shared E. H. Phillips· 1 shared E. Phillips· 1 shared G. Mancinelli· 1 shared J. K. Kitajewski· 1 shared J. Rehman· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

X. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Impaired Barrier Integrity of the Skeletal Muscle Vascular Endothelium Drives Progression of Cancer Cachexia

Y.-M. Kim, M. A. Sanborn, X. Wang, G. Mancinelli, S. Chakraborty, S. Vijeth, P. Gajwani, P. Grippo, S. S.-Y. Lee, T. Valyi-Nagy, P. T. Toth, K. Valyi-Nagy, J. Rehman

This study identifies impaired vascular endothelial integrity in skeletal muscle as a driver of cancer cachexia and shows that restoring endothelial PGC1 can prevent muscle loss.

Nature Cancer · May 26, 2025Peer-reviewedCancer Biology

Increased multiplexity in optical tissue clearing-based 3D immunofluorescence microscopy of the tumor microenvironment by LED photobleaching

J. Zheng, Y.-c. Wu, E. Phillips, X. Wang, S. S.-Y. Lee

This paper introduces an LED photobleaching method to enhance 3D immunofluorescence microscopy multiplexity for tumor microenvironment analysis, achieving 8-plex imaging.

bioRxiv · Nov 29, 2023Cancer Biology

Three-dimensional spatial quantitative analysis of cardiac lymphatics in the mouse heart

E. H. Phillips, V. P. Bindokas, D. Jung, J. Teamer, J. K. Kitajewski, R. J. Solaro, B. M. Wolska, S. S.-Y. Lee

The paper develops a 3D lightsheet microscopy workflow and image analysis pipeline to study cardiac lymphatic vessel morphology in HCM mouse hearts, identifying pathological changes in the right atrium.

bioRxiv · Feb 1, 2023Pathology