Author

P. Gajwani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. Rehman· 4 shared P. T. Toth· 3 shared G. Schwarz· 2 shared L. Wang· 2 shared S. Krantz· 2 shared Y.-M. Kim· 2 shared Z. Ye· 2 shared A. V. Karginov· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCell Biology

J. Rehman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Impaired Barrier Integrity of the Skeletal Muscle Vascular Endothelium Drives Progression of Cancer Cachexia

Y.-M. Kim, M. A. Sanborn, X. Wang, G. Mancinelli, S. Chakraborty, S. Vijeth, P. Gajwani, P. Grippo, S. S.-Y. Lee, T. Valyi-Nagy, P. T. Toth, K. Valyi-Nagy, J. Rehman

This study identifies impaired vascular endothelial integrity in skeletal muscle as a driver of cancer cachexia and shows that restoring endothelial PGC1 can prevent muscle loss.

Nature Cancer · May 26, 2025Peer-reviewedCancer Biology

Parallel Activation of Src and Hif1α Increases Localized Glycolytic ATP Generation for Re-assembly of Endothelial Adherens Junctions

L. Wang, P. Gajwani, P. Chaturvedi, Z. Hong, Z. Ye, G. Schwarz, N. Pohl-Avila, A.-M. Ray, S. Krantz, P. T. Toth, D. E. Leckband, A. V. Karginov, J. Rehman

This study shows that Src and Hif1α activation increases glycolytic ATP production near endothelial adherens junctions, facilitating their re-assembly after injury.

bioRxiv · Nov 11, 2022 · PreprintCell Biology

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses

P. Gajwani, L. Wang, S. Srivastava, Z. Ye, Y.-M. Kim, S. Krantz, D. Wang, C. Tiruppathi, P. T. Toth, J. Rehman

This study identifies endothelial mitophagy as a source of mitochondrial formyl proteins that activate neutrophils and contribute to lung inflammation.

bioRxiv · Aug 7, 2022 · PreprintCell Biology

Glycolysis Inhibition Regulates Endothelial Junctions by Perturbing Actin and Focal Adhesions

D. Leckband, J. Rehman, G. Schwarz, P. Gajwani

This study shows that glycolysis inhibition reduces VE-cadherin junction tension by disrupting actin and focal adhesions, impacting endothelial barrier integrity.

bioRxiv · Oct 22, 2020 · PreprintBiophysics