Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
S. Yuan, S. Hahn, M. P. Miller, S. Sanker, M. Calderon, M. Sullivan, A. Dosunmu-Ogunbi, M. Fazzari, Y. Li, M. Reynolds, K. Wood, C. St. Croix, D. Stolz, E. Cifuentes-Pagano, P. Navas, , A. C. Straub
This study shows CYB5R3 modulates NOX4 activity via coenzyme Q to reduce endothelial inflammation, with in vivo and in vitro evidence of their interaction and functional dependency.
Redox Biology · Nov 1, 2021Peer-reviewedCell Biology