An interaction hub on Ndc80 complex facilitates dynamic recruitment of Mps1 to yeast kinetochores to promote accurate chromosome segregation
E. J. Parnell, E. Jenson, M. P. Miller
bioRxiv · Nov 7, 2023 · PreprintCell Biology
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M. P. Miller
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2020-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
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Stu2 has an essential kinetochore role independent of regulating microtubule dynamics
A. A. Abouelghar, J. S. Carrier, J. R. Torvi, E. Jenson, C. Jones, B. Gangadharan, E. A. Geyer, L. Rice, B. Lagesse, G. Barnes, M. P. Miller
This study identifies Stu2's essential kinetochore function independent of its microtubule dynamics regulation through separation-of-function mutants and artificial tethering.
bioRxiv · Sep 9, 2022 · PreprintCell Biology
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
S. Yuan, S. Hahn, M. P. Miller, S. Sanker, M. Calderon, M. Sullivan, A. Dosunmu-Ogunbi, M. Fazzari, Y. Li, M. Reynolds, K. Wood, C. St. Croix, D. Stolz, E. Cifuentes-Pagano, P. Navas, , A. C. Straub
This study shows CYB5R3 modulates NOX4 activity via coenzyme Q to reduce endothelial inflammation, with in vivo and in vitro evidence of their interaction and functional dependency.
Redox Biology · Nov 1, 2021Peer-reviewedCell Biology
Structural Basis of Stu2 Recruitment to Yeast Kinetochores
J. A. Zahm, M. G. Stewart, J. S. Carrier, S. C. Harrison, M. P. Miller
This study identifies the structural basis of Stu2 recruitment to yeast kinetochores by showing its interaction with the Ndc80 complex, which is essential for tension-dependent stabilization of kinetochore-microtubule attachments.
bioRxiv · Oct 31, 2020Biochemistry