Author

P. Navas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Bogdanova· 1 shared A. Burgardt· 1 shared A. C. Straub· 1 shared A. Cogolludo· 1 shared A. Cortes· 1 shared A. Dosunmu-Ogunbi· 1 shared A. Girona· 1 shared A. Izquierdo-Alvarez· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Bogdanova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells

L. Pelosi, L. Morbiato, A. Burgardt, F. Tonello, A. K. Bartlett, R. M. Guerra, K. K. Ferizhendi, M. A. Desbats, B. Rascalou, M. Marchi, L. Vazquez-Fonseca, C. Agosto, G. Zanotti, M. Roger-Margueritat, M. Alcazar-Fabra, , F. Pierrel

This study identifies COQ4 as catalyzing the oxidative decarboxylation of the C1 carbon in CoQ biosynthesis in eukaryotic cells.

bioRxiv · Nov 13, 2023Biochemistry

Mitochondrial defects leading to arrested spermatogenesis and ferroptosis in a mouse model of Leigh Syndrome

E. Radaelli, C.-A. Assenmacher, E. Banerjee, F. Manero, S. Khiati, A. Girona, G. Lopez-Lluch, P. Navas, M. Spinazzi

This study shows that PARL deficiency in mice causes testicular atrophy and male infertility due to ferroptosis in spermatocytes, independent of neurodegeneration.

bioRxiv · Nov 22, 2022Cell Biology

Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation

S. Yuan, S. Hahn, M. P. Miller, S. Sanker, M. Calderon, M. Sullivan, A. Dosunmu-Ogunbi, M. Fazzari, Y. Li, M. Reynolds, K. Wood, C. St. Croix, D. Stolz, E. Cifuentes-Pagano, P. Navas, , A. C. Straub

This study shows CYB5R3 modulates NOX4 activity via coenzyme Q to reduce endothelial inflammation, with in vivo and in vitro evidence of their interaction and functional dependency.

Redox Biology · Nov 1, 2021Peer-reviewedCell Biology

Mitochondrial Na+ controls oxidative phosphorylation and hypoxic redox signalling

P. Hernansanz-Agustin, C. Choya-Foces, S. Carregal-Romero, E. Ramos, T. Oliva, T. Villa-Pina, L. Moreno, A. Izquierdo-Alvarez, J. D. Cabrera-Garcia, A. Cortes, A. V. Lechuga-Vieco, P. Jadiya, E. Navarro, E. Parada, A. Palomino-Antolin, , A. Martinez-Ruiz

This study shows that mitochondrial Na+ acts as a second messenger regulating OXPHOS and ROS production through interactions with phospholipids during hypoxia.

bioRxiv · Oct 31, 2019Biochemistry