Author

S. Violante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. R. Cross· 2 shared S. Houten· 2 shared T. Dodatko· 2 shared A. L. Zuckerman· 1 shared A. Sabovic· 1 shared C. Argmann· 1 shared C. Yao· 1 shared C. Yu· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

J. R. Cross

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Author profile →

3 papers

Recent·Most cited

Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1

S. Khamrui, T. Dodatko, R. Wu, J. Leandro, A. Sabovic, S. Violante, J. R. Cross, E. Marsan, K. Kumar, R. DeVita, M. B. Lazarus, S. Houten

The paper characterizes the human SUGCT enzyme, determines its structure, and identifies inhibitors that may lead to new treatments for glutaric aciduria type 1.

bioRxiv · Feb 7, 2024Biochemistry

A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells

M. L. Heacock, E. N. Abdulaziz, X. Pan, A. L. Zuckerman, S. Violante, C. Yao, J. R. Cross, V. Cracan

This paper introduces a genetically encoded tool to increase the NADH/NAD+ ratio in mammalian cells and characterizes its metabolic and transcriptomic effects.

bioRxiv · Sep 20, 2022 · PreprintBioengineering

Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis

P. Ranea-Robles, S. Violante, C. Argmann, T. Dodatko, D. Bhattacharya, H. Chen, C. Yu, S. L. Friedman, M. Puchowicz, S. Houten

This study investigates the role of EHHADH in DCA β-oxidation and its impact on hepatic cholesterol homeostasis in mice, finding that EHHADH deficiency leads to 3-hydroxydicarboxylic aciduria and altered cholesterol synthesis.

bioRxiv · Mar 2, 2021Physiology