Author

Samuel C. Agius

Monash University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Organism:human· 1

Frequent Co-Authors

Chen DavidovichiD· 2 shared Evan HealyiD· 2 shared Edwina McGlinniD· 1 shared Emma H. Gail· 1 shared Guizhi Sun· 1 shared Jan ManentiD· 1 shared Jeanette M. J. Rientjes· 1 shared Jihane Homman‐LudiyeiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Chen DavidovichORCID

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2 papers

Recent·Most cited

Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains

Samuel C. Agius, Marion Boudes, Evan Healy, Yoona Kim, Yi-Cheng Chang, Melanie Murray, Jan Manent, Jeanette M. J. Rientjes, Zhihao Lai, Sophie Nixon, Jihane Homman‐Ludiye, Vitalina Levina, Edwina McGlinn, Chen Davidovich

The paper shows that PRC2 subunits JARID2 and PALI1 mimic H3K27me3 to restrict Polycomb domain spread by antagonizing PRC2 activity in vivo and stem cells.

Molecular Cell · Mar 1, 2026Peer-reviewedMolecular Biology

The apparent loss of PRC2 chromatin occupancy as an artefact of RNA depletion

Evan Healy, Qi Zhang, Emma H. Gail, Samuel C. Agius, Guizhi Sun, Michael J. Bullen, Varun Pandey, Partha Pratim Das, Jose Maria Polo, Chen Davidovich

The paper shows that RNase A treatment during ChIP-seq falsely reduces PRC2 chromatin occupancy signals, revealing limitations in using this method to study RNA-dependent chromatin regulation.

Cell Reports · Feb 27, 2024Peer-reviewedMolecular Biology