Partha Pratim Das

The paper quantifies splice-site usage variation across species and identifies intronic hexamer sequences as key determinants of splice-site choice through GWAS and experimental validation.

The paper shows that RNase A treatment during ChIP-seq falsely reduces PRC2 chromatin occupancy signals, revealing limitations in using this method to study RNA-dependent chromatin regulation.

The paper identifies cis- and trans-regulatory elements of Oct4 in mESCs using ctSCAN-SMS, showing CREs are more active and conserved than TREs.

The paper identifies combinatorial functions of histone demethylases in gene regulation of mouse embryonic stem cells by analyzing their genome-wide binding patterns.