Sayoko Fujimura

MEIOSIN retains an intrinsic STRA8-independent activity that drives meiotic entry across vertebrate evolution

The paper shows MEIOSIN has a STRA8-independent activity that drives meiotic entry in vertebrates, with different effects in zebrafish and mice.

MAP7-driven microtubule remodeling builds the Sertoli apical domain that supports timely meiotic progression

This study identifies MAP7 as a key regulator of microtubule remodeling in Sertoli cells, essential for apical domain formation and timely meiotic progression in mouse testes.

Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions

This study identifies HSF5 as a male germ cell-specific factor critical for meiotic prophase progression beyond pachytene under non-stress conditions.

Meiosis-specific ZFP541 repressor complex promotes meiotic prophase exit during spermatogenesis

This study identifies a ZFP541-KCTD19 repressor complex that promotes meiotic prophase exit in spermatogenesis by suppressing transcriptional regulators and chromatin modifiers.

A meiosis-specific factor MRM/C19orf57 modulates localization of RAD51 and DMC1 recombinases to DSBs in mouse meiotic recombination

This study identifies C19orf57 as a factor that modulates RAD51 and DMC1 localization to DSBs during meiotic recombination in mice, impacting DSB repair and male fertility.