Author

Seunghwan Choi

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Won‐Kyu JuiD· 3 shared Yury I. MilleriD· 3 shared Guy A PerkinsiD· 2 shared Jungsu KimiD· 2 shared Keun-Young KimiD· 2 shared Mark H. EllismaniD· 2 shared Muna PoudeliD· 2 shared Robert Neal WeinrebiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Won‐Kyu JuORCID

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3 papers

Recent·Most cited

Therapeutic AIBP expression contributes to synaptic preservation and vision restoration against glaucomatous neuroinflammation

Tonking Bastola, Sinwoo Hwang, Ziyao Shen, Soo-Ho Choi, Seunghwan Choi, Esther Jang, Muna Poudel, Keun-Young Kim, Yury I. Miller, Robert Neal Weinreb, Won‐Kyu Ju

This paper shows that AAV2-hAIBP preserves retinal ganglion cells and visual function in glaucoma without lowering intraocular pressure by targeting neuroinflammation through the AIBP-TLR4 axis.

bioRxiv · Oct 12, 2026 · PreprintNeuroscience

Restoring AIBP expression in the retina provides neuroprotection in glaucoma

Won‐Kyu Ju, Keun-young Kim A, Tonking Bastola, Ziyao Shen, Seunghwan Choi, Guy A Perkins, Sinwoo Hwang, Jungsu Kim, Jin-Woo Kwon, Muna Poudel, Sébastien Phan, Fan Xia, Shuizhen Shi, Hyunkyung Cho, Hua Liu, , Soo-Ho Choi

This study shows that restoring AIBP expression in glaucomatous retinas protects retinal ganglion cells and reduces neuroinflammation in mouse models.

Molecular Therapy · May 9, 2025Peer-reviewedNeuroscience

AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease

Yi Sak Kim, Soo‐Ho Choi, Keun-Young Kim, Juliana Maria Navia Pelaez, Guy A Perkins, Seunghwan Choi, Jungsu Kim, Nicolaus Nazarenkov, Robert A. Rissman, Won‐Kyu Ju, Mark H. Ellisman, Yury I. Miller

This study shows that AIBP regulates TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease, reducing neuroinflammation and neurodegeneration.

Journal of Neuroinflammation · Sep 28, 2024Peer-reviewedNeuroscience