Soo‐Ho Choi

This study shows that microglial cholesterol accumulation worsens neuronal synaptic vulnerability to amyloid-beta in Alzheimer's disease.

This study shows that TLR-4 enhances TRPV1-mediated calcium influx in DRG neurons through PKA signaling, contributing to pain hypersensitivity.

The paper identifies AKAP1 as a critical regulator of mitochondrial and synaptic homeostasis in glaucoma, showing its role in neuroprotection and axon regeneration through gene therapy in mouse models.

The paper examines AIBP expression in Alzheimer's disease by analyzing human brain tissue and mouse models, finding a progressive loss of astrocytic AIBP with disease progression.

This study shows that AIBP regulates TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease, reducing neuroinflammation and neurodegeneration.

This study shows that loss of AKAP1 leads to Drp1 dephosphorylation, mitochondrial fragmentation, and RGC dysfunction in glaucoma, suggesting AKAP1 as a therapeutic target.