Author

Shannon Hull

Dana-Farber Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Kevin M. HaigisiD· 2 shared Alison W. Tisdale· 1 shared Anna Idelevich· 1 shared Benjamin Hanna· 1 shared Bing ShuiiD· 1 shared Carlie SigeliD· 1 shared Christian William JohnsoniD· 1 shared Clarence YappiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Kevin M. HaigisORCID

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2 papers

Recent·Most cited

Cooperativity between Ras pathway mutations in colonic tumorigenesis

Christian William Johnson, Anna Idelevich, Bing Shui, Alison W. Tisdale, Eve O’Donoghue, Joshua Cook, Shannon Hull, Moon Hee Yang, Shikha Sheth, Elizabeth M. Terrell, Stefânia Bovo Minto, Deborah K. Morrison, Scott Kopetz, Rona D. Yaeger, Kevin M. Haigis

This study shows that specific KRAS mutations, like A59E, cooperate with other genetic alterations in CRC and affect response to EGFR inhibitors.

bioRxiv · Sep 5, 2025 · PreprintCancer Biology

Baseline expression of c-Myc defines the tissue specificity of oncogenic K-Ras

Olesja Popow, Qing Yu, Clarence Yapp, Shannon Hull, João A. Paulo, Benjamin Hanna, Shidong Xu, Yanan Kuang, Carlie Sigel, Cloud Peter Paweletz, Steven P. Gygi, Kevin M. Haigis

The paper shows that low baseline c-Myc expression restricts oncogenic K-Ras activity in tissues, and this can be reversed by increasing c-Myc in the liver.

bioRxiv · Jul 21, 2025 · PreprintCancer Biology