Author

Shayla Kopriva

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Corinne E Bovee· 2 shared Siming LiuiD· 2 shared Spencer J. PeacheeiD· 2 shared Yumi ImaiiD· 2 shared Aditya Joglekar· 1 shared Aidan Freshly· 1 shared Anamika Vikram· 1 shared Beyza N. Ilerisoy· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Corinne E Bovee

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2 papers

Recent·Most cited

Perilipin 5 Phosphorylation is Dispensable for Upregulation of Hepatic Lipid Metabolism Genes upon Fasting but Required for Insulin Receptor Substrate 2 Expression in Male Mice

Corinne E Bovee, Ryan P Grandgenett, Michelle B. Trevino, Sucharita M. Dutta, Spencer J. Peachee, Shayla Kopriva, Farakh Haider, Siming Liu, Gourav Bhardwaj, Christie M. Penniman, Brian Timothy O'Neill, Yumi Imai

This study investigates the role of PLIN5 phosphorylation in mice, finding it dispensable for lipid metabolism gene upregulation during fasting but necessary for IRS2 expression in males.

Endocrinology · Apr 12, 2025Peer-reviewedMolecular Biology

Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets

Siming Liu, Israel J Wipf, Aditya Joglekar, Aidan Freshly, Corinne E Bovee, Lucy Kim, Syreine Richtsmeier, Spencer J. Peachee, Shayla Kopriva, Anamika Vikram, Dalal El Ladiki, Fatma S. Ilerisoy, Beyza N. Ilerisoy, Gianna Sagona, Claudia Jun, , Yumi Imai

This study shows that PLIN2 regulates lipophagy in beta cells to prevent fatty acid accumulation in mitochondria, which impairs insulin secretion and mitochondrial function.

bioRxiv · Nov 17, 2024 · PreprintMolecular Biology