Author

Takashi Kudo

University of TsukubaORCID 0000-0001-5477-7235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

Ryo FujitaiD· 3 shared Ryosuke TsujiiD· 3 shared Shunya Sadaki· 3 shared Masato WatanabeiD· 2 shared Takuto HayashiiD· 2 shared Ana C Ricardo· 1 shared Angela R. SaboiD· 1 shared Atsushi Kubo· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Ryo FujitaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Continuous Large Maf Activity Maintains Fast Myofiber Identity and Multicellular Homeostasis in Adult Skeletal Muscle

Shunya Sadaki, Ryosuke Tsuji, Tatsuya Matsumoto, Takuto Hayashi, Takehito Sugasawa, Takashi Kudo, Naoki Horii, Kei-ichiro Yasunaga, Edgar Jauliac, Pascal Maire, Yusuke Ono, Satoru Takahashi, Ryo Fujita

bioRxiv · Oct 13, 2026 · PreprintCell Biology

Spatial proteomics identifies altered thick ascending limb cells as drivers of kidney disease through uromodulin retention

Azuma Nanamatsu, George J. Rhodes, William S. Bowen, Angela R. Sabo, Shehnaz Khan, Mahla Asghari, Dillen L Wischmeier, Daria Barwinska, Takashi Kudo, Azusa Tomioka, Hiroaki Sakaue, Atsushi Kuno, Ana C Ricardo, James Phillip Lash, Katherine R. Tuttle, , Tarek M. El‐Achkar

This study identifies altered thick ascending limb cells with UMOD retention as drivers of CKD using spatial proteomics and shows reducing UMOD retention attenuates CKD development.

bioRxiv · Oct 12, 2026 · PreprintCell Biology

Cardiac-Detargeted MyoAAV Enables Systemic Nrl-Mediated Fast Myofiber Remodeling and Hypertrophy Across Multiple Skeletal Muscles

Keisuke Hitachi, Shunya Sadaki, Masato Watanabe, Ryosuke Tsuji, Atsushi Kubo, Yuki Yamasaki, Yuri Kiyofuji, Masafumi Inui, Takashi Kudo, Tomohiko Suzuki, Satoru Takahashi, Kunihiro Tsuchida, Ryo Fujita

This paper develops a modified MyoAAV vector that detargets cardiac expression, enabling safe systemic induction of fast myofiber remodeling and hypertrophy in skeletal muscles.

bioRxiv · Apr 23, 2026 · PreprintCell Biology

Large MAF Transcription Factors Reawaken Evolutionarily Dormant Fast-Glycolytic Type IIb Myofibers in Human Skeletal Muscle

Shunya Sadaki, Ryosuke Tsuji, Takuto Hayashi, Masato Watanabe, Ryoto Iwai, Gu Wenchao, Ekaterina A. Semenova, Султанов Ринат Илгизович, Желанкин Андрей Викторович, Edward V. Generozov, Ildus I. Ahmetov, Iori Sakakibara, Koichi Ojima, Hidetoshi Sakurai, Masafumi Muratani, , Ryo Fujita

This study identifies large MAF transcription factors as inducers of type IIb myofibers in humans, enhancing glycolytic capacity and correlating with power training.

Skeletal Muscle · Jul 26, 2025Peer-reviewedCell Biology