Author

Sherman M. Weissman

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Caiming CheniD· 2 shared Guanchuan LiniD· 2 shared Junxiao ZhangiD· 2 shared Liyao MaiiD· 2 shared Sadie L. MarjaniiD· 2 shared Xinghua PaniD· 2 shared Yulong ZhangiD· 2 shared Alexander Eckehart UrbaniD· 1 shared

Activity by Year

2016-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersGenomics

Caiming ChenORCID

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Author profile →

4 papers

Recent·Most cited

msCNVS: medium throughput single cell copy number variation sequencing with barcoded library construction free of preamplification toward clinical implementation

Guanchuan Lin, Bin Peng, Caiming Chen, Zhanying Dong, Mengchang Xu, Jinyu Gao, Jie Yu, Bei Jia, Chen Luo, Rui Hua, Changtai Xiao, Linlin Wang, Liyao Mai, Yulong Zhang, Yuanfang Lu, , Xinghua Pan

msCNVS enables efficient CNV profiling of rare clinical samples through barcoded single-cell library construction without preamplification.

bioRxiv · Apr 1, 2024 · PreprintGenomics

Shortcut barcoding and early pooling for scalable multiplex single-cell reduced-representation CpG methylation sequencing at single nucleotide resolution

Liyao Mai, Zebin Wen, Yulong Zhang, Yu Gao, Guanchuan Lin, Zhiwei Lian, Xiang Yang, Jingjing Zhou, Xianwei Lin, Chaochao Luo, Wanwan Peng, Caiming Chen, Jiajia Peng, Duolian Liu, Sadie L. Marjani, , Xinghua Pan

The paper introduces msRRBS, a scalable single-cell methylation sequencing method, achieving high read mapping rates and cost efficiency for analyzing methylation patterns in multiple cell lines and cancer models.

Nucleic Acids Research · Oct 4, 2023Peer-reviewedGenomics

Local and global chromatin interactions are altered by large genomic deletions associated with human brain development

Xianglong Zhang, Ying Zhang, Xiaowei Zhu, Carolin Purmann, Michael Seamus Haney, Thomas Ward, Arineh Khechaduri, Jie Yao, Sherman M. Weissman, Alexander Eckehart Urban

The paper investigates how large genomic deletions affect chromatin interactions and states in human brain development using Hi-C and ChIP-Seq analyses.

Nature Communications · Dec 11, 2018Peer-reviewedGenetics

Methods for detecting co-mutated pathways in cancer samples to inform treatment selection

Tingting Jiang, Uri Shaham, Fabio Parisi, Ruth Halaban, Anton Mikhailovich Safonov, Harriet M. Kluger, Sherman M. Weissman, Joseph T. Chang, Yuval Kluger

The paper develops a method to detect co-mutated pathways in cancer samples and identifies enriched pathway pairs across six cancer types, suggesting potential mechanisms for immune evasion.

bioRxiv · Oct 22, 2016 · PreprintBioinformatics