Shichen Shen

Yck2 links mitochondrial function and pH homeostasis to cell wall remodeling and antifungal susceptibility in Cryptococcus neoformans

This study identifies Yck2's role in linking mitochondrial function, pH homeostasis, and cell wall remodeling in Cryptococcus neoformans, revealing mechanisms behind its impact on antifungal susceptibility.

Leveraging Dynamic Stability to Infer Regulation in Protein-Protein Interaction Networks: A Study of Infectious Vulnerability in COPD.

The paper infers regulatory relationships in protein-protein interaction networks from proteomic data to identify oxidative stress pathways linked to infectious vulnerability in COPD.

Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination

This study shows that loss of Phb2 in Schwann cells disrupts myelination and dysregulates key transcription factors essential for peripheral nerve development.

Dynamic Phosphorylation Regulates Eukaryotic Translation Initiation Factor 4A Activity During the Cell Cycle

This study identifies phosphorylation sites on eIF4A that regulate its activity during different cell cycle phases, showing how phosphorylation modulates translation and cell cycle progression.

Arginine methylation of Puf4 drives diverse protein functions

This study shows that arginine methylation of Puf4 regulates its functions in post-transcriptional gene regulation in Cryptococcus neoformans.