Joseph J. Barbi

Translation Inhibition by Rocaglamide A Enhances Susceptibility of Yeasts to Caspofungin

The paper shows that inhibiting translation initiation helicases with Rocaglamide A increases yeast susceptibility to caspofungin, suggesting combination therapy could reduce resistance.

p38 blockade reverses the immune suppressive tumor microenvironment in metastatic breast cancer

This study shows that blocking p38 reduces metastasis in breast cancer by reversing immune suppression in the tumor microenvironment, primarily through effects on CD8+ T cells and myeloid cells.

Dynamic Phosphorylation Regulates Eukaryotic Translation Initiation Factor 4A Activity During the Cell Cycle

This study identifies phosphorylation sites on eIF4A that regulate its activity during different cell cycle phases, showing how phosphorylation modulates translation and cell cycle progression.