Sarah E. Walker

Protein Arginine Methylation of the Translation Initiation Factor eIF1A Increases Usage of a Near-cognate Start Codon

The paper identifies eIF1A methylation sites and shows that methylation at R13 and R14 improves start codon recognition fidelity in yeast.

Translation Inhibition by Rocaglamide A Enhances Susceptibility of Yeasts to Caspofungin

The paper shows that inhibiting translation initiation helicases with Rocaglamide A increases yeast susceptibility to caspofungin, suggesting combination therapy could reduce resistance.

Analysis of Divergent Gene Expression between HPV+ and HPV- Head and Neck Squamous Cell Carcinoma Patients

This study compares gene expression profiles between HPV+ and HPV- HNSCC using RNA-seq data from the PanCancer Atlas 2018, identifying distinct molecular features associated with HPV status.

Neuronal activation in the axolotl brain promotes spinal cord regeneration

This study identifies a population of neurons in the axolotl brain that, when activated by tail amputation, promote spinal cord regeneration by stimulating hormone production.

Dynamic Phosphorylation Regulates Eukaryotic Translation Initiation Factor 4A Activity During the Cell Cycle

This study identifies phosphorylation sites on eIF4A that regulate its activity during different cell cycle phases, showing how phosphorylation modulates translation and cell cycle progression.

Regulation of stem cell identity by miR-200a during spinal cord regeneration

The paper shows that miR-200a regulates mesodermal cell fate during spinal cord regeneration by repressing brachyury expression in axolotls.

The NTD of Eukaryotic Initiation Factor 4B Drives Yeast Translational Control in Response to Urea

This study identifies the N-terminal domain of eIF4B as critical for yeast growth under urea stress by enhancing translation of mRNAs with structured 5' UTRs.