ERK builds a population of short-lived nascent adhesions that produce persistent edge protrusion and cell migration
Andrew P. Shepherd, Keith R. Carney, Majid Rostami, Jakaria Shawon, Andrew Elliott, Shiela C. Samson, Sangyoon J. Han, Michelle C. Mendoza
This study shows ERK regulates nascent adhesion dynamics by promoting both assembly and disassembly, creating short-lived adhesions that support persistent cell migration.
Proceedings of the National Academy of Sciences · Jun 15, 2026Peer-reviewedCell Biology